Computational heart modelling

Using ARCHER to develop large computational models that mathematically represent the chemistry, electrics, and mechanics of the heart.

The heart is a complex organ, with electrical activation and mechanical contraction working together to pump blood around the body. In situations where either of these systems fail or stop working in synchrony, without treatment heart failure can follow.

Understanding how this complex multiphysics and multiscale system works, is regulated, and fails, is crucial to improving patient diagnosis, optimising procedures, and predicting outcomes.

A personalised approach to computational heart modelling

Researchers at King’s College London, the Medical University of Graz and Oslo University Hospital have applied ARCHER to simulating individual patients’ hearts in order to better understand patient physiology, pathology, and treatment outcomes. They have exploited the computational power of ARCHER to develop large computational models that mathematically represent the chemistry, electrics, and mechanics of the heart.

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